CBD vs. CBDa (Benefits and Effects)

Have you heard about the compounds CBD and CBDa? Despite their names being similar, these two cannabinoid molecules have very different properties. In this blog post, we will discuss the differences between CBD and CBDa to help you understand what makes each unique. We'll compare how they act in the body and examine some of their potential health benefits. By understanding the differences between these two substances, you can make a more informed decision when choosing which is suitable for your needs.

What is CBD?

CBD, which stands for cannabidiol, is a unique part of the cannabis plant. It is one of more than 100 compounds found in the cannabis plant. Unlike other parts of the plant, like THC, it does not make you feel "high." Instead, research has shown that CBD may have many possible therapeutic uses. 

For instance, CBD reduces pain and stress and works as an anti-inflammatory. It is also known to help improve sleep, reduce anxiety, and even fight certain forms of cancer. 

What is CBDa?

CBDa stands for cannabidiolic acid. It is the acidic form of CBD found in raw cannabis plants before they are heated or cured. Like CBD, it does not make you feel "high." Research has shown that it can provide many potential therapeutic benefits similar to CBD. 

For example, CBDa is anti-inflammatory and reduces pain and stress levels. It may also have anti-tumor properties, helping fight certain cancers. Additionally, some claim that CBDa is more effective than CBD at reducing chemotherapy-related nausea and vomiting.

CBD vs. CBDA Effects:

What effects does CBD have on the body?

CBD interacts with the endocannabinoid system in the body, acting as a regulator to keep homeostasis. It has been found to have anti-inflammatory, anti-anxiety, and antidepressant properties. It can also help improve sleep quality, reduce stress levels, and promote overall well-being.

What effects does CBDa have on the body?

CBDa is thought to act similarly to CBD regarding therapeutic benefits. Studies show that it has anti-inflammatory and antioxidant effects, making it helpful in fighting inflammation-related conditions like arthritis and fibromyalgia. Additionally, preliminary research suggests that CBDa may be more effective than CBD at reducing nausea associated with chemotherapy treatments. Lastly, some studies indicate that CBDa may help manage seizures, but more research is needed. 

In conclusion, CBDa has many potential therapeutic benefits and is receiving increasing interest from the scientific community due to its various health-promoting effects. It may be an alternative or complementary treatment for multiple conditions, including inflammation, nausea, anxiety, and sleep disorders. However, further research is needed to fully understand how it works in the body and explore its potential clinical applications. 

Despite their similarities, CBD and CBDA may relieve distinct symptoms in different ways because of how they are metabolized in the body. And researchers are just beginning to uncover CBDA's unique advantages.

How is CBDa turned into CBD?

Cannabidiol acid (CBDa) is turned into the well-known cannabidiol (CBD) through decarboxylation, a chemical reaction that removes a carboxyl group from CBDa. This conversion can be done through heating or light exposure, with heat being the most common method. 

Once CBDa is converted to CBD, it binds to cannabinoid receptors in the body and modulates how cells respond to different signals. By interacting with specific receptor sites in the brain and throughout the body, CBD helps regulate bodily functions such as pain perception, cognitive function, anxiety levels, sleep patterns, and more. It may affect neurotransmitter activity, inflammation levels, and immune response. 

Overall, CBDa has been found to have many of the same potential therapeutic benefits as CBD; however, further research is still needed to determine the full extent of its effects. CBDa may play an essential role in supporting overall health and wellness. 

Whether someone prefers CBDa or CBD, both compounds offer unique therapeutic benefits that can be harnessed in various ways. They both provide potential relief from symptoms related to anxiety, pain, and inflammation without any psychoactive side effects. Investigating how they differ and how these differences can benefit the user is an exciting prospect for future research! 

Advantages of CBD vs. CBDa

Cannabidiol (CBD) and cannabidiolic acid (CBDA) are both critical phytocomponents in the cannabis plant, with many purported health benefits. CBDA is the most abundant form of CBD present in raw or minimally heated cannabis plants, but when exposed to higher temperatures, it converts into CBD. 

CBD is known for its ability to reduce pain and inflammation, while CBDA has been found to have efficacy in treating nausea and vomiting. In addition, both compounds can help alleviate symptoms related to anxiety and depression. CBD has also been studied for its potential antipsychotic effects. 

Research suggests that CBDA may have an increased bioavailability compared to CBD, meaning it can be better absorbed by the body and substantially affect the user. A recent study also found that CBDA was more effective at inhibiting COX-2 enzymes than CBD, which could lead to fewer side effects when taken as a supplement. 

As more research is done on both compounds, understanding the differences between CBD vs. CBDA can benefit users seeking relief from various health conditions. With further development of cannabis products containing higher levels of CBDA, users may find improved efficacy in their treatment regimens. 

Which is better for me? CBD vs. CBDa

With the recent surge in the use of hemp-derived products, it is no surprise that cannabidiol (CBD) and its acidic precursors, collectively known as "CBDa," are being discussed more frequently. However, there are some distinct advantages to using one form over the other, depending on a person's needs.

  • CBD vs. CBDa may provide faster relief from anxiety or discomfort than its acidic forerunner. CBD is quickly absorbed into the bloodstream, while CBDa must first be converted to its active form, which results in a slower onset of action. For this reason, CBD is generally preferred for acute symptoms that need faster relief.
  • CBDa may be preferable as an anti-inflammatory agent due to its higher levels of antioxidants and polyphenols. Thus far, research suggests CBDa may be more effective at decreasing inflammation than CBD. Unlike CBD, CBDa has not been through the decarboxylation process that destroys some beneficial compounds. 
  • CBDa is considerably more difficult to find since it is only produced when raw cannabis is gently heated and has been shown to retain more significant amounts of beneficial microbial compounds. CBD, on the other hand, is much easier to find since it is more widely available and readily extracted from hemp plants. 
  • The most significant downside of CBDA is that it degrades pretty quickly when exposed to heat, air, and light. This means that it must be stored and handled very carefully to preserve its therapeutic benefits. 

When selecting a supplement, choosing CBD vs. CBDa is ultimately up to the user. While both compounds offer potential health benefits, more research is needed to determine the most effective for particular ailments. Ultimately,


The debate between CBD and CBDa can continue, but both offer distinct benefits. In terms of medicinal qualities, CBDa is still the preferred choice among many due to its anti-inflammatory properties and ability to help reduce nausea. On the other hand, CBD has been known to assist with anxiety relief and sleep-related issues. Ultimately, both are excellent supplements for well-being and should be taken in tandem whenever possible. 

Additionally, it is essential to remember that different people will respond differently to these compounds. 

Therefore, the best way to determine which works best for your needs is by consulting a physician or other medical professional who can guide proper dosing and potential side effects.

Leave a comment

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

Subscribe to our newsletter

Be the first to know about new collections and exclusive offers.